Research conducted by the members of the Chair focuses on both scientific and application aspects. The faculty focus on the development of various technologies for the extraction of plant raw materials, as well as assessment of the content and properties of biologically active compounds in the obtained extracts. Analyses of the cytotoxicity of extracts and isolated substances are carried out on selected cell lines. Research is also conducted to assess changes in gene expression in cells treated with the obtained extracts.
The Chair faculty also develop recipes and technologies for the production of prototype cosmetics containing the obtained active substances or extracts, and determine the substances’ impact on the safety of cosmetics. Physicochemical and biochemical assessment of the obtained cosmetic preparations is also conducted, as well as studies of transepidermal transport of bioactive substances contained in model formulations.
Research financed from the means of the Ministry of Science and Higher Education:
Subject: Innovative raw materials for application in the medical, pharmaceutical and cosmetic industries
Project Manager: Zofia Nizioł-Łukaszewska, Ph.D., Eng.
The main aim of the project is to assess in detail the mechanisms of action of the tested substances, including their antioxidant, chelating and anti-inflammatory properties. Raw materials with the most desirable properties will be applied in pharmaceutical, cosmetic and medical preparations. The project involves the implementation of experimental research in the form of a series of laboratory experiments, followed by a detailed description of their results. The research aims to determine the mechanism of action of selected substances in cell-free and cellular systems. A range of raw materials will be analysed which may have practical application in the medical, pharmaceutical and cosmetic industries.
Implementation period: 2019 – 2020
Subject: New hydrogel biomaterials for dermatology and cosmetology – synthesis, characterization and biological evaluation
Project Manager: Martyna Zagórska-Dziok, M.Sc.
The main goal of the project is to obtain new hydrogels for dermatological and cosmetological applications. The developed hydrogel matrices contain biologically active substances which can stimulate skin repair processes. The project includes structural and physicochemical analyses of the obtained polymer biomaterials. Additionally, biological studies are conducted to assess the effect of the tested biomaterials on the metabolism and proliferation of skin cells: keratinocytes and fibroblasts. The influence of the developed hydrogels on the level of intra- and extracellular reactive oxygen species and the antioxidant capacity of the developed matrices is also assessed. Moreover, the project assesses the antibacterial properties of the analysed hydrogels against bacterial strains responsible for skin diseases.
Implementation period: 2019-2020